David S Goldstein Selected Research

Pure Autonomic Failure

1/2021	Differential abnormalities of cerebrospinal fluid dopaminergic versus noradrenergic indices in synucleinopathies.
12/2020	Cardioselective peripheral noradrenergic deficiency in Lewy body synucleinopathies.
11/2020	"Sick-but-not-dead": multiple paths to catecholamine deficiency in Lewy body diseases.
10/2020	The "Sick-but-not-Dead" Phenomenon Applied to Catecholamine Deficiency in Neurodegenerative Diseases.
10/2020	Cardiac sympathetic innervation and vesicular storage in pure autonomic failure.
1/2020	The catecholaldehyde hypothesis: where MAO fits in.
10/2019	Long-term trends in myocardial sympathetic innervation and function in synucleinopathies.
1/2018	Orthostatic heart rate changes in patients with autonomic failure caused by neurodegenerative synucleinopathies.
1/2018	Roles of cardiac sympathetic neuroimaging in autonomic medicine.
1/2018	Spectrum of abnormalities of sympathetic tyrosine hydroxylase and alpha-synuclein in chronic autonomic failure.

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David S Goldstein Research Topics

Disease

76	Parkinson Disease (Parkinson's Disease) 01/2022 - 08/2002
43	Orthostatic Hypotension (Postural Hypotension) 01/2021 - 11/2002
36	Multiple System Atrophy 01/2021 - 07/2002
33	Pure Autonomic Failure 01/2021 - 08/2002
20	Synucleinopathies 01/2022 - 02/2007
19	Parkinsonian Disorders (Parkinsonism) 01/2021 - 09/2003
17	Pheochromocytoma 01/2018 - 03/2002
15	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 02/2008
14	Dementia (Dementias) 11/2020 - 11/2011
12	Neoplasms (Cancer) 01/2010 - 03/2002
10	Movement Disorders (Movement Disorder) 01/2020 - 11/2003
10	Hypertension (High Blood Pressure) 02/2016 - 05/2002
8	Autonomic Nervous System Diseases (Dysautonomia) 01/2020 - 06/2003
8	Dizziness (Lightheadedness) 05/2015 - 02/2002
7	Menkes Kinky Hair Syndrome (Menkes Disease) 09/2018 - 02/2008
6	Lewy Body Disease (Lewy Body Dementia) 01/2018 - 03/2009
5	Orthostatic Intolerance 01/2019 - 11/2002
5	REM Sleep Behavior Disorder 01/2019 - 11/2011
5	Anosmia 01/2019 - 01/2010
4	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 06/2003
4	Cognitive Dysfunction 01/2022 - 04/2011
3	Heart Failure 03/2022 - 11/2002
3	Syncope (Fainting) 01/2019 - 01/2003
3	dopamine beta hydroxylase deficiency 01/2019 - 06/2012
3	Hypothermia 09/2008 - 01/2002
3	von Hippel-Lindau Disease (von Hippel Lindau Disease) 05/2007 - 10/2005
3	Multiple Endocrine Neoplasia Type 2a (MEN 2) 05/2007 - 10/2005
3	Vasovagal Syncope 09/2006 - 06/2002
2	Neurodevelopmental Disorders 01/2018 - 08/2009
2	Disease Progression 11/2017 - 11/2003
2	Hypotension (Low Blood Pressure) 08/2009 - 09/2006
2	Paraganglioma (Paragangliomas) 04/2005 - 01/2003
2	Tachycardia (Tachyarrhythmias) 11/2004 - 11/2002
2	Schizophrenia (Dementia Praecox) 11/2004 - 08/2002
2	Shy-Drager Syndrome 06/2004 - 07/2002
1	Inflammation (Inflammations) 01/2022
1	Rare Diseases (Rare Disease) 10/2020
1	COVID-19 01/2020
1	Hemorrhage 01/2020

Drug/Important Bio-Agent (IBA)

43	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2022 - 02/2002
36	CatecholaminesIBA 01/2022 - 01/2002
33	Dopamine (Intropin)FDA LinkGeneric 01/2022 - 11/2003
23	hydroxide ionIBA 01/2021 - 06/2003
18	alpha-SynucleinIBA 01/2021 - 04/2004
16	Biomarkers (Surrogate Marker)IBA 01/2022 - 02/2007
15	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2005
10	SynucleinsIBA 01/2022 - 04/2004
9	Epinephrine (Adrenaline)FDA LinkGeneric 09/2008 - 01/2003
7	3,4-dihydroxyphenylacetaldehydeIBA 06/2021 - 12/2012
6	Neurotransmitter Agents (Neurotransmitter)IBA 10/2020 - 11/2002
6	CatecholsIBA 01/2019 - 06/2003
6	CopperIBA 09/2018 - 02/2008
5	TyramineIBA 02/2016 - 10/2004
5	3,4-dihydroxyphenylglycolIBA 01/2010 - 11/2004
5	NormetanephrineIBA 04/2005 - 01/2003
4	Aldehyde DehydrogenaseIBA 01/2022 - 08/2014
4	Vesicular Monoamine Transport Proteins (Vesicular Monoamine Transporter)IBA 01/2022 - 12/2004
4	3,4-Dihydroxyphenylacetic AcidIBA 01/2018 - 08/2009
4	Dihydroxyphenylalanine (Dopa)IBA 09/2015 - 08/2004
4	Messenger RNA (mRNA)IBA 01/2015 - 10/2005
4	Levodopa (L Dopa)FDA LinkGeneric 10/2014 - 11/2003
4	MetanephrineIBA 04/2005 - 01/2003
3	Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA 01/2022 - 03/2003
3	Pharmaceutical PreparationsIBA 01/2022 - 06/2005
3	Monoamine Oxidase (MAO)IBA 11/2017 - 02/2016
3	EnzymesIBA 01/2016 - 08/2003
3	Edrophonium (Tensilon)FDA LinkGeneric 05/2015 - 10/2004
3	Adrenergic Agents (Adrenergic Drugs)IBA 01/2013 - 05/2002
3	Glucagon (Glukagon)FDA Link 01/2010 - 09/2008
3	Yohimbine (Yocon)IBA 11/2008 - 07/2002
3	Aromatic-L-Amino-Acid DecarboxylasesIBA 12/2004 - 03/2003
3	Adrenergic Receptors (Adrenergic Receptor)IBA 05/2003 - 06/2002
2	Norepinephrine Plasma Membrane Transport Proteins (Norepinephrine Transporter)IBA 01/2022 - 10/2005
2	RotenoneIBA 01/2022 - 04/2015
2	VaccinesIBA 01/2020 - 01/2020
2	DroxidopaIBA 01/2019 - 05/2010
2	Selegiline (E250)FDA LinkGeneric 11/2017 - 09/2016
2	Cholinergic Agents (Cholinergics)IBA 05/2015 - 10/2004
2	AldehydesIBA 03/2015 - 01/2012
2	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 07/2014 - 09/2003
2	Adenosine Triphosphatases (ATPase)IBA 02/2013 - 05/2002
2	Copper-Transporting ATPasesIBA 09/2012 - 08/2009
2	Transcription Factors (Transcription Factor)IBA 07/2012 - 08/2006
2	fluorodopa F 18IBA 11/2011 - 01/2010
2	ProdrugsIBA 01/2011 - 05/2010
2	catechol (pyrocatechol)IBA 08/2009 - 12/2004
2	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 08/2009 - 03/2009
2	AntibodiesIBA 03/2009 - 12/2006
2	Trimethaphan (Trimetaphan)IBA 11/2008 - 10/2004
2	Isoproterenol (Isoprenaline)FDA LinkGeneric 11/2008 - 09/2008
2	AminesIBA 04/2005 - 01/2003
2	Amino Acids FDA Link 12/2004 - 08/2003
2	FludrocortisoneIBA 08/2003 - 11/2002
1	CytokinesIBA 01/2022
1	Atomoxetine Hydrochloride (Strattera)FDA LinkGeneric 01/2022
1	OsteoprotegerinIBA 01/2022
1	GoldIBA 01/2020

Therapy/Procedure

25	Sympathectomy (Sympathectomies) 01/2019 - 08/2002
17	Denervation 01/2019 - 09/2003
5	Therapeutics 03/2022 - 08/2003